Effects of Different Tunnel Methods in PICC Catheterization

Recruiting now · Not applicable

Conditions studied: PICC Line Placement, PICC-associated Thrombosis

In brief

This prospective randomized controlled trial compares the effectiveness and safety of one-needle and two-needle tunneling techniques for peripherally inserted central catheter (PICC) placement, aiming to identify the optimal tunneling method to reduce catheter-related complications.

Key facts

Study ID

NCT07594704

Run by

Sun Yat-sen University

People needed

284

Starts

2026-04-01

Expected to finish

2026-07-30

Last updated by the study team

2026-05-22

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged between 18 and 75 years old;
• Educational level of primary school or above, with basic listening, speaking, reading and writing abilities, and capable of completing the questionnaire independently;
• Receiving tunneled PICC catheterization for the first time, with 4Fr single-lumen solo PICC catheter indwelling;
• Able to attend regular PICC maintenance at our hospital as scheduled after catheterization;
• Voluntarily participate in this study and sign the informed consent form for this study as well as the informed consent form for PICC catheterization.

You may not qualify if…

• Patients with coagulation dysfunction (INR > 1.5 / PLT < 50×10⁹/L);
• Pregnant or lactating women;
• Patients with BMI < 18.5 kg/m²;
• Patients receiving PICC catheterization via lower extremity veins;
• Patients with known or suspected allergy to components of PICC catheters.

Where it is running

• Sun Yat-sen University Cancer Center — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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