Morphometric Markers of the Effectiveness of Micropulse Cyclophotocoagulation

Recruiting now · Not applicable

Conditions studied: Glaucoma

In brief

This prospective study aims to evaluate morphometric markers of treatment response following micropulse transscleral cyclophotocoagulation (MP-CPC) in patients with glaucoma. The study will assess changes in choroidal thickness and the choroidal vascularity index (CVI) measured by optical coherence tomography (OCT) before treatment, 3-7 days after the procedure, and 1 month postoperatively. Intraocular pressure (IOP) will be measured at the same time points. The correlation between changes in choroidal thickness, the choroidal vascularity index (CVI) and IOP reduction will be analyzed. Additionally, the study seeks to determine the minimal baseline choroidal thickness associated with a clinically significant hypotensive effect after MP-CPC.

Key facts

Study ID: NCT07592923
Run by: Kazakh Eye Research Institute
People needed: 20
Starts: 2026-05-18
Expected to finish: 2026-08-18
Last updated by the study team: 2026-05-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Decision to treat by MP-CPC Laser
Patients diagnosed with Glaucoma
Patients aged 18 years old and above
Glaucoma that is inadequately controlled on medical therapy

You may not qualify if…

Patients age less than 18 years
Patients unable or unwilling to provide informed consent to participate in the study
Patients potentially unavailable for follow up visits
Patients with significant scleral thinning
Patients with ocular infection, inflammation or intraocular surgery in the study eye 2 months prior to enrollment in the study
Albino patients that have no iris pigmentation

Where it is running

Kazakh Eye Research Institute — Almaty, Kazakhstan (enrolling)

Full record on ClinicalTrials.gov

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