Intraoperative CO₂ (Carbon Dioxide)

Starting soon · Not applicable

Conditions studied: Wound Edges

In brief

To evaluate whether intraoperative fractionated CO₂ laser treatment of surgical wound edges improves postoperative scar appearance compared with untreated wound edges following Mohs micrographic surgery (MMS).

Key facts

Study ID

NCT07592468

Run by

Baylor Research Institute

People needed

50

Starts

2026-05-01

Expected to finish

2027-12-01

Last updated by the study team

2026-05-20

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-89 years
• Diagnosis of cutaneous malignancy treated with MMS
• Surgical defect suitable for primary linear or flap closure with adequate length to permit split-scar design
• Ability to understand and provide informed consent

You may not qualify if…

• Pregnancy
• Inability to provide informed consent
• Non-English speaking patients
• History of abnormal wound healing (e.g., keloid disorder)
• Active infection at the surgical site
• Immunosuppression felt to significantly impair wound healing
• Use of isotretinoin within the past 6 months
• Prior radiation therapy to the surgical site
• Patients belonging to vulnerable populations including prisoners, children, or individuals unable to consent

Where it is running

• Baylor University Medical Center — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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