"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia

Recruiting now · Phase 2/Phase 3

Conditions studied: Pain, Postoperative, Opioid Use, Laparotomy

In brief

Transversus abdominis plane block is a regional anesthetic technique which blocks the abdominal neural afferents by introducing local anesthetic into the neuro-fascial plane between the internal oblique and the transversus abdominis muscle and gives analgesia from the skin to parietal peritoneum. There are studies showing evidence of improved post operative analgesia with addition of adjuvants such as dexmedetomidine or dexamethasone in comparison with plane local anesthesia in terms of time to rescue analgesia and the overall quantity of analgesic used post operatively.

Key facts

Study ID

NCT07590752

Run by

Sahiwal medical college sahiwal

People needed

96

Starts

2024-03-03

Expected to finish

2026-07-04

Last updated by the study team

2026-05-15

Who can join

Age: 25 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients undergoing laparotomy.
• Patients aged 25 to 65 years.
• Both genders.
• Patients with ASA Class I, II.

You may not qualify if…

• Patients who do not give consent.
• Patients with Comorbidities like DM, HTN, CKD, CLD.
• Patients with bleeding disorders.
• Infection at site of injection.
• Allergy to any drug, local anaesthetic, or other drugs used.
• Patients with polytrauma.

Where it is running

• Sahiwal Medical College — Sahiwal, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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