Periosteal Muscular Flap in Reconstruction of Small and Medium Sized Defects at Floor of the Mouth

Starting soon · Not applicable

Conditions studied: Maxillofacial Reconstruction

In brief

Background: Rebuilding head and neck defects is a chief challenge to the maxillofacial surgeons especially after cancer resection, trauma, infection and craniofacial deformities. Earlier, the use of obturators for many years has been a successful treatment plan. However, recently several surgical modalities are available for the restoration of such defects as locoregional or microvascular free flaps. Aim: To assess the reliability of the lateral periosteal-muscular flap in the reconstruction of small and medium sized floor of the mouth defects. Main outcome: To evaluate functional outcomes (Including speech, tongue mobility, deglutition, flap viability), pain, complications such as trismus, flap necrosis, dehiscence, infection, fistula formation or donor site morbidity and aesthetic outcomes. Mean harvesting time and flap dimensions will be recorded.

Key facts

Study ID

NCT07590427

Run by

Alexandria University

People needed

20

Starts

2026-06-01

Expected to finish

2027-06-01

Last updated by the study team

2026-05-15

Who can join

Age: 30 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients requiring reconstruction of small and medium sized FOM defects.

You may not qualify if…

• Previous neck dissection.
• Previous radiotherapy in the maxillofacial region.
• Uncontrolled diseases that may contraindicate the surgery

Where it is running

• Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt — Alexandria, Azarita, Egypt

Full record on ClinicalTrials.gov

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