Mulligan Mobilization in Lateral Elbow Tendinopathy

Starting soon · Not applicable · Has a placebo group

Conditions studied: Lateral Elbow Tendinopathy (Tennis Elbow)

In brief

The aim of this study is to investigate the short-, medium-, and long-term effects of Mulligan Mobilization with Movement (MWM) added to an exercise program on pain, functionality, and biomechanical parameters in individuals with lateral elbow tendinopathy, compared to sham mobilization and exercise-only interventions. The primary hypothesis is that the addition of true MWM to exercise will result in greater improvements in pain intensity, grip strength, pressure pain threshold, kinesiophobia, wrist joint position sense, and the mechanical properties of the extensor muscles compared to placebo (sham MWM) and exercise alone. This study is designed as a three-arm randomized placebo-controlled trial. A total of 45 participants will be allocated to one of three groups: MWM plus exercise, sham MWM plus exercise, and exercise alone. Assessments will be conducted at baseline, immediately post-intervention, and at 3- and 6-month follow-ups. The primary outcome measure is pain intensity. Secondary outcomes include functionality, grip strength, pressure pain threshold, kinesiophobia, wrist proprioception, and the mechanical properties of the extensor carpi radialis brevis muscle assessed using Myoton. This study aims to determine the effects of manual therapy independent of placebo and to evaluate the sustainability of these effects over time. Additionally, by objectively assessing the mechanical and proprioceptive characteristics of the muscle-tendon unit alongside clinical outcomes, the study is expected to provide a novel contribution to the literature. The findings are anticipated to enhance the understanding of the mechanisms underlying conservative treatment approaches in lateral elbow tendinopathy and to support evidence-based clinical decision-making.

Key facts

Study ID

NCT07589725

Run by

Istanbul Kent University

People needed

45

Starts

2026-05-15

Expected to finish

2027-10-01

Last updated by the study team

2026-05-15

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Inclusion Criteria
• Age between 18 and 60 years
• Presence of unilateral lateral elbow pain and tenderness for at least 3 months
• Diagnosis of lateral elbow tendinopathy confirmed by the following four criteria:
• Local tenderness over the lateral epicondyle
• Positive Cozen's test
• Positive Maudsley's test
• Positive Mill's stretch test

You may not qualify if…

• History of surgery around the elbow
• History of elbow dislocation, fracture, or extensor tendon rupture
• History of fracture of the humerus, ulna, or radius within the past year
• Receipt of any treatment for LET within the past 6 months (e.g., physiotherapy, exercise, manual therapy, dry needling, orthosis)
• Presence of cervical referred pain and/or radiculopathy (positive Spurling test)
• Signs of peripheral nerve involvement
• Corticosteroid injection within the past 6 months
• History of rheumatologic disease
• Presence of cancer or tumor

Where it is running

• Istanbul Unıversity Cerrahpasa, Faculty of Health Sciences — Istanbul, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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