Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy

Starting soon · Not applicable

Conditions studied: Intertransverse Process Block, Mtapa Block, Laparoscopic Cholecystectomy, Postoperative Pain, Regional Anaesthesia

In brief

This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.

Key facts

Study ID

NCT07589491

Run by

Antalya City Hospital

People needed

60

Starts

2026-11-15

Expected to finish

2027-10-30

Last updated by the study team

2026-06-16

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 18-65 years
• ASA physical status I-III
• Scheduled for elective laparoscopic sleeve gastrectomy
• Body mass index (BMI) 18-35 kg/m²
• Ability to understand and use the patient-controlled analgesia (PCA) device
• Ability to provide written informed consent

You may not qualify if…

• Refusal to participate
• Allergy to local anesthetics
• Infection at the injection site
• Coagulopathy or ongoing anticoagulant therapy
• Chronic opioid use or opioid dependence
• Severe hepatic or renal insufficiency
• Pregnancy or breastfeeding
• Cognitive impairment or inability to communicate pain scores
• Body mass index (BMI) >35 kg/m²

Full record on ClinicalTrials.gov

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