CLIME-CJD: A Multimodal Study
Enrolling by invitation
Conditions studied: Creutzfeldt-Jakob Disease (CJD) | Prion Disease
In brief
Creutzfeldt-Jakob disease (CJD) is a rare and rapidly progressive neurological disorder. This study aims to describe and summarize the key features of CJD by looking back at medical records of patients who were diagnosed with CJD at our hospital. The researchers will collect information from routine clinical evaluations, including patients' symptoms, blood tests, cerebrospinal fluid analysis, brain imaging (such as MRI and PET), and electroencephalography (EEG). By analyzing these data together, the study hopes to provide a clearer picture of how CJD presents in routine clinical practice. This may help doctors recognize the disease more quickly in the future. No new tests or treatments will be given to patients. All data are collected from existing medical records.
Key facts
- Study ID
- NCT07589283
- Run by
- First Affiliated Hospital of Fujian Medical University
- People needed
- 150
- Starts
- 2022-01-01
- Expected to finish
- 2031-12-01
- Last updated by the study team
- 2026-05-15
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of definite or probable Creutzfeldt-Jakob Disease (CJD) according to the established WHO diagnostic criteria
- Available medical records covering at least one of the following: clinical history, peripheral blood test results, cerebrospinal fluid (CSF) analysis findings, brain MRI reports/images, or EEG reports
- Hospitalized or evaluated at the participating institution during the study period
You may not qualify if…
- Alternative diagnosis confirmed that explains all clinical features (e.g., autoimmune encephalitis, rapidly progressive dementia due to other causes)
- Incomplete medical records with no relevant clinical, laboratory, imaging, or EEG data available
- Patient or legal representative declined the use of medical records for research purposes (where applicable according to local regulations)
Where it is running
- The First Affiliated Hospital of Fujian Medical University — Fuzhou, China
Full record on ClinicalTrials.gov
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