AI-GF-GNW on Prolonged Grief Reactions

Starting soon · Not applicable

Conditions studied: Artificial Intelligence (AI), Prolonged Grief Symptoms, Depression - Major Depressive Disorder, Anxiety, Disabilities

In brief

Prolonged Grief Disorder (PGD) is a severe, disabling condition characterized by intense yearning and difficulty accepting the reality of loss, which significantly impairs the academic and psychosocial functioning of bereaved adolescents. While Grief-Focused Cognitive Behavioral Therapy (GF-CBT) is effective, its high cost and resource-intensive nature limit its accessibility for adolescents in mainland China. Grief-Focused Guided Narrative Writing (GF-GNW) offers a scalable, low-cost alternative that facilitates memory integration. Furthermore, integrating Artificial Intelligence (AI) to provide personalized, structured feedback has the potential to simulate therapist functions and enhance intervention efficacy. However, the specific efficacy of AI-assisted feedback in this context remains empirically unvalidated. This parallel randomized controlled trial aims to examine the effectiveness of AI-assisted GF-GNW (AI-GF-GNW) in treating Chinese adolescents (aged 10-19) with subclinical PGD, compared to a no-feedback NF-GF-GNW group and a free writing group. Primary outcomes include PGD symptom severity, while secondary outcomes assess depression, anxiety, and daily functioning. We hypothesize that both active intervention arms will significantly alleviate PGD and related symptoms compared to the free writing group, and that the AI-GF-GNW group will demonstrate a significantly greater reduction in symptoms and functional impairment than the NF-GF-GNW group.

Key facts

Study ID

NCT07589088

Run by

Peking University

People needed

126

Starts

2026-05-25

Expected to finish

2027-05-01

Last updated by the study team

2026-05-15

Who can join

Age: 10 and older, up to 19. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Junior and senior high school students currently studying in Chinese Mainland, aged 10-19;
• Between 6 and 60 months prior to the experimental period, experienced the death of a significant family member or close friend or close friend;
• The total symptom score of PG-13-R is between 20-29 points;
• Ability to write and understand written guidelines, to use the mobile phone to interact with AI;
• Consent to participate in the study.

You may not qualify if…

• Diagnosed or previously diagnosed with mental illness
• The bereavement time does not meet the time window
• PG-13-R score is not within the range
• At present, there is suicidal ideation or recent severe self harm behavior (Reynolds' Suicidal Ideation Questionnaire, SIQ-JR-4>0), and a crisis intervention hotline is provided when necessary.
• Has received other grief counseling or is currently taking psychiatric medication within the past month

Where it is running

• Peking University — Beijing, Beijing Municipality, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.