Pain Assessment During Rapid Sequence Induction

Recruiting now

Conditions studied: Rapide Sequence Induction, Tracheal Intubation, Nociception, General Anesthesia

In brief

Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception using the Analgesia Nociception Index (ANI) during this procedure. This monocentric prospective observational study aims to describe the impact of RSI on pain measured by ANI, and to explore early complications (desaturation, hypotension, regurgitation) and factors associated with pain and complications. 150 patients undergoing RSI in the visceral surgery operating room at CHPG Monaco will be analyzed.

Key facts

Study ID

NCT07588165

Run by

Centre Hospitalier Princesse Grace

People needed

150

Starts

2026-05-21

Expected to finish

2028-05-01

Last updated by the study team

2026-05-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >= 18 years
• Patient requiring tracheal intubation after rapid sequence induction in the visceral surgery operating room
• Pain monitoring by Analgesia Nociception Index (ANI) as part of general anesthesia

You may not qualify if…

• Patient with atrial fibrillation at the time of intubation following rapid sequence induction
• Patient on long-term beta-blocker therapy

Where it is running

• Centre Hospitalier Princesse Grace — Monaco, Monaco (enrolling)

Full record on ClinicalTrials.gov

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