Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery

Recruiting now · Not applicable

Conditions studied: Coronary Artery Bypass Graft (CABG), Postoperative Pain, Sternotomy

In brief

Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery. This prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting. Patients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.

Key facts

Study ID

NCT07587320

Run by

Saglik Bilimleri Universitesi

People needed

56

Starts

2026-01-01

Expected to finish

2026-09-01

Last updated by the study team

2026-05-14

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 18 and 80 years
• Scheduled for elective isolated coronary artery bypass grafting (CABG) with saphenous vein graft harvesting
• ASA physical status II-IV
• Ability to provide written informed consent

You may not qualify if…

• Known coagulopathy or contraindication to regional anesthesia
• Use of anticoagulant therapy precluding regional block
• Known allergy to local anesthetics
• Local infection at planned block sites
• Chronic opioid use or chronic pain syndrome
• Emergency surgery
• Redo sternotomy
• Severe neurological disorder affecting pain assessment

Where it is running

• University of Health Sciences, Diyarbakir Gazi Yasargil Training and Research Hospital — Diyarbakır, Diyarbakır, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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