China-NINE Cohort：Neuroimmune Network in Elderly / Neurodegeneration
Enrolling by invitation
Conditions studied: Cognitive Dysfunction, Cognitive Dysfunction, Cognitive Disorder, Parkinson's Disease (PD)
In brief
This is an observational study aimed at understanding the cognitive, functional, and behavioral characteristics of Chinese patients with cognitive impairment, exploring the underlying mechanisms, and providing evidence for early diagnosis, treatment, and care of cognitive disorders including dementia. Eligible participants will undergo a series of assessments and examinations, including cognitive and memory scale tests, routine blood tests, ApoE genetic testing, cerebrospinal fluid testing, brain MRI, functional MRI, and FDG-PET/AV45-PET scans when necessary. Additional samples such as saliva, nasal secretions, and stool may also be collected. Most evaluations are provided free of charge to support diagnosis and treatment guidance. Participation is voluntary. All personal information and research data will be kept confidential. Potential benefits include access to expert clinical care and free cognitive assessments for disease evaluation. Possible inconveniences include time commitment and temporary discomfort during examinations; medical support will be provided if needed.
Key facts
- Study ID
- NCT07586501
- Run by
- Yantai Yuhuangding Hospital
- People needed
- 260
- Starts
- 2026-01-16
- Expected to finish
- 2029-01-01
- Last updated by the study team
- 2026-05-14
Who can join
Age: 55 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Participants with clinically diagnosed cognitive impairment. Patients with clinically diagnosed Parkinson's disease. Healthy control participants.
You may not qualify if…
- Central nervous system infection, head trauma, epilepsy, multiple sclerosis, or other major neurological disorders.
- Malignant tumors. Family history of genetic disorders.
Where it is running
- Yantai Yuhuangding Hospital — Yantai, Shandong, China
- Yantai Yuhuangding Hospital — Yantai, China
Full record on ClinicalTrials.gov
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