Stereotactic Body Radiotherapy Boost Versus Simultaneous Integrated Boost to Pelvic Nodes Among Patients Receiving Radical Chemoradiation in Carcinoma Cervix

Recruiting now · Not applicable

Conditions studied: Stage IIIC

In brief

Cervical cancer is a significant cause of morbidity and mortality among women worldwide. Radiotherapy, in combination with chemotherapy or as a standalone treatment, is an effective treatment option for cervical cancer. However, traditional radiotherapy has its limitations, such as the potential for damage to surrounding healthy tissues. Stereotactic Body RadioTherapy (SBRT) is a newer radiotherapy technique that delivers high doses of radiation to the tumor with minimal damage to the surrounding tissues. This study aims to evaluate the safety of Stereotactic Body RadioTherapy to involved node in cervical cancer.

Key facts

Study ID

NCT07585929

Run by

All India Institute of Medical Sciences

People needed

150

Starts

2024-11-20

Expected to finish

2026-11-19

Last updated by the study team

2026-05-29

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Patients with stage IIIC cervical cancer
• No previous pelvic radiation therapy or surgery
• Eastern Cooperative Oncology Group (ECOG) performance status of 0-2

You may not qualify if…

• Patients with stage I or stage II or stage IV disease.
• Patients with prior malignancies or active autoimmune diseases
• Uncontrolled medical comorbidity

Where it is running

• All India Institute of Medical Sciences — Delhi, National Capital Territory of Delhi, India (enrolling)
• Karun Kamboj — Delhi, National Capital Territory of Delhi, India (enrolling)
• National Cancer Institute, All India Institute of Medical Sciences, New Delhi, India — New Delhi, New Delhi, India (enrolling)

Full record on ClinicalTrials.gov

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