Effect of High-Intensity Laser Therapy on Femoral Cartilage in Knee Osteoarthritis
Starting soon · Not applicable
Conditions studied: Osteoarthritis (OA) of the Knee, Osteoarthitis
In brief
This clinical trial will evaluate the effects of High-Intensity Laser Therapy (HILT) on femoral cartilage thickness and other clinical outcomes in people with knee osteoarthritis. Participants aged 40 to 60 years with grade II or III knee osteoarthritis will be randomly assigned to receive either HILT plus conventional physiotherapy or conventional physiotherapy alone. Both groups will receive 12 treatment sessions on alternate days for 4 weeks. The study will assess changes in cartilage thickness using ultrasound, as well as improvements in pain, knee movement, muscle strength, and daily function. Findings from this research may help improve physiotherapy treatment strategies for patients with knee osteoarthritis.
Key facts
- Study ID
- NCT07584603
- Run by
- University of Lahore
- People needed
- 58
- Starts
- 2026-07-01
- Expected to finish
- 2027-05-10
- Last updated by the study team
- 2026-05-13
Who can join
Age: 40 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male and female participants aged 40-60 years.
- Diagnosed with knee osteoarthritis (Kellgren-Lawrence grade II or III).
- Knee pain for at least 3 months.
- Visual Analogue Scale (VAS) score ≥ 3.
- Willing to provide written informed consent and comply with treatment and follow-up schedule.
You may not qualify if…
- History of knee surgery or traumatic knee injury.
- Inflammatory arthritis (e.g., gout, psoriatic arthritis).
- History of cancer or psychiatric illness.
- Cognitive disorders (e.g., Parkinson's disease, Alzheimer's disease).
- Severe comorbidities limiting exercise (e.g., severe COPD, heart failure, cerebrovascular event).
- Hip or ankle joint disability.
- Intra-articular knee injection within the past 3 months.
Where it is running
- London Aesthetics and Rejuvenation Center — Lahore, Punjab Province, Pakistan
Full record on ClinicalTrials.gov
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