Dexamethasone in Tick-borne Encephalitis

Recruiting now · Phase 3 · Has a placebo group

Conditions studied: Tick-Borne Encephalitis

In brief

The purpose of this study is to investigate the efficacy of dexamethasone in patients with tick-borne encephalitis.

Key facts

Study ID

NCT07584525

Run by

University Medical Centre Ljubljana

People needed

200

Starts

2024-05-03

Expected to finish

2030-09-30

Last updated by the study team

2026-05-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age 18 years or older and
• clinical signs and symptoms of meningoencephalitis or meningomyelitis and
• cerebrospinal pleocytosis and
• serological confirfmation of tick-borne encephalitis virus infection

You may not qualify if…

• pregnancy or
• severe neurological impairment befor tick-borne encephalitis or
• systemic corticosteroid treatment in the past 30 days or
• allergy to corticosteroids or
• immunosuppresive condition or therapy such as HIV with CD4 < 200/ml, organ or bone marrow transplant, receiving chemotherapy, radiotherapy or any other immunosuppresive therapy, primary immunodeficiency, hematological maliganncy or
• ventricular shunt or
• endoscopically documented peptic gastric ulcer in the past six months or gastrointestinal bleeding with hemoglobin drop ≥ 20 units or
• uncontrolled diabetes with hyperglicemia or
• antiviral therapy with rilpivirin

Where it is running

• University Medical Centre Ljubljana — Ljubljana, Slovenia (enrolling)

Full record on ClinicalTrials.gov

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