The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial
Starting soon · Phase 2 · Has a placebo group
Conditions studied: Surgical Wounds, Mohs Surgery
In brief
The goal of this study clinical trial is to learn if topical timolol can accelerate healing and improve the cosmetic appearance of surgical wounds on the scalp following Mohs surgery. It will include Geisinger patients 18 year or older who undergo Mohs surgery of the scalp with planned wound healing by secondary intent. The main questions in aim to answer are: 1. Compare wound healing speed between patients treated with topical timolol and those receiving standard wound care only. 2. Compare cosmetic outcomes using topical timolol and standard wound care. 3. Evaluate the impact of topical timolol on the number of unplanned follow-up visits and calls related to delayed wound healing. Participants will be asked use either topical timolol or use standard wound care to treat their Mohs surgery scalp wound. They will follow-up around 4, 8 and 12 weeks.
Key facts
- Study ID
- NCT07583862
- Run by
- Geisinger Clinic
- People needed
- 40
- Starts
- 2026-07-01
- Expected to finish
- 2029-03-01
- Last updated by the study team
- 2026-05-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age: Adults aged 18 years and older. Condition: Patients who have undergone Mohs surgery on the scalp. Consent: Ability to provide informed consent. Willingness to Participate: Willingness to comply with study procedures and attend follow-up visits.
- Healing by Secondary Intention: Wounds intended to heal by secondary intention.
You may not qualify if…
- Known allergy or sensitivity to timolol or any components of the study medication.
- Bronchial asthma or history of bronchial asthma
- Severe chronic obstructive pulmonary disease (COPD)
- Sinus bradycardia
- Second or third-degree atrioventricular block
- Overt heart failure
- Cardiogenic shock
- Under the influence of opioids or benzodiazepines at time of enrollment
- History of scarring alopecia in area of Mohs wound
- History of radiation treatment
- Patients being treated for recurrent tumors
Where it is running
- Geisinger Dermatology Woodbine — Danville, Pennsylvania, United States
Full record on ClinicalTrials.gov
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