Out-of-office Monitoring for Rhythms Of Normal Versus Atrial Fibrillation

Enrolling by invitation · Not applicable

Conditions studied: Atrial Fibrillation (AF), Hypertension (HTN), High Blood Pressure

In brief

The goal of this clinical trial is to learn if screening for atrial fibrillation (AFib), a common irregular heart rhythm, through daily home blood pressure monitoring will decrease the time to atrial fibrillation diagnosis in older adults with hypertension. The main question it aims to answer is: \-- Does introducing screening for AFib using a blood pressure monitor with AFib detection technology decrease time to AFib diagnosis in patients with high blood pressure, compared to usual care using a conventional home blood pressure monitor with no AFib detection? Participants will participate in two phases of the study: (1) clinical trial and (2) the registry. During the 6-month clinical trial period, participants will be asked to: * Take blood pressure measurements twice daily * Answer short weekly mobile app-based surveys * If assigned, complete continuous heart monitoring for 2 weeks and complete 1 blood test During the 12-month registry period, participants will be asked to: * Take blood pressure measurements twice daily * Answer monthly mobile app-based surveys Researchers will compare standard blood pressure measurements and AFib screening blood pressure measurements to see if there is a difference in the time to AFib diagnosis and other cardiovascular events. Participants will participate in two phases of the study: (1) trial and (2) the registry. During the 6-month trial period, participants will be asked to: * Take daily blood pressure measurements * Answer short weekly mobile app-based surveys * If assigned, complete continuous heart monitoring for 2 weeks and complete 1 blood test During the 12-month registry period, participants will be asked to: * Take daily blood pressure measurements * Answer monthly mobile app-based surveys

Key facts

Study ID

NCT07582523

Run by

University of California, San Francisco

People needed

1910

Starts

2026-04-01

Expected to finish

2029-04-01

Last updated by the study team

2026-05-13

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Hypertensive* patients aged 60 years or older living in the United States who meet at least one of the following criteria:
• ≥70 years old
• BMI ≥30kg/m2
• CHA2DS2-VASc ≥3 (excluding Female sex)

You may not qualify if…

• Current or prior diagnosis of atrial fibrillation (AFib), atrial flutter, or atrial tachycardia
• Receiving anticoagulation therapy
• History of skin allergies to adhesive patches
• Open wound or skin inflammation, such as eczema, in the chest region.
• Inability to wear the patch ECG monitor or apply the monitor by herself/himself or with the help of a caregiver
• Individuals who are currently using home medical devices or wearable devices capable of detecting atrial fibrillation and are unwilling to refrain from using such AF detection device features during the randomized controlled trial (RCT) phase of the study
• People who have a mailing address in Alaska, Hawaii, or a U.S. territory

Where it is running

• UCSF Medical Center at Parnassus — San Francisco, California, United States

Full record on ClinicalTrials.gov

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