Network Effects of Left M1 rTMS: A TMS-EEG Study

Recruiting now · Not applicable

Conditions studied: Cortical Plasticity

In brief

This study investigates the modification of connectivity patterns in response to one session of active repetitive transcranial magnetic stimulation (rTMS) applied to the primary motor cortex. Transcranial magnetic stimulation (TMS) will be applied to elicit electroencephalography (EEG) responses in healthy volunteers. TMS-evoked potentials (TEPs) will be recorded before and after the rTMS session and will serve as a reflection of cortical connectivity to TMS. Four cortical targets will be stimulated for TMS-EEG assessment: left primary motor cortex, right primary motor cortex, left premotor cortex, and right occipital cortex.

Key facts

Study ID

NCT07580989

Run by

Aalborg University

People needed

20

Starts

2026-05-01

Expected to finish

2027-12-31

Last updated by the study team

2026-05-14

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy men and women
• Speak and understand English

You may not qualify if…

• Drug addiction defined as the use of cannabis, opioids or other drugs
• Previous neurologic, musculoskeletal or mental illnesses
• Lack of ability to cooperate
• History of chronic pain or current acute pain
• Contraindications to rTMS application (history of epilepsy, metal in the head or jaw etc.).
• Failure to pass the "TASS questionnaire" (TASS = Transcranial Magnetic Stimulation Adult Safety Screen)

Where it is running

• Aalborg University — Gistrup, Denmark (enrolling)

Full record on ClinicalTrials.gov

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