SUPPORT-HEART-PK: Effectiveness, Implementation, and Economic Evaluation of Implementation, and Theory-Based Digital Self-Management Intervention for Heart Failure Management

Starting soon · Not applicable

Conditions studied: Heart Failure, Chronic Heart Failure (CHF)

In brief

Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system. Existing adherence interventions in Pakistan are limited, mostly educational, and rarely guided by behavioural theory, implementation science, or economic evaluation. Therefore, a culturally appropriate, RE-AIM-informed autonomy-competence intervention is needed to improve medication adherence and quality of life among heart failure patients in Pakistan, while also assessing implementation feasibility and cost-effectiveness for future scale-up.

Key facts

Study ID

NCT07580508

Run by

Universiti Putra Malaysia

People needed

870

Starts

2026-07-25

Expected to finish

2026-09-15

Last updated by the study team

2026-07-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• Diagnosed heart failure for at least 6 months
• Prescribed ≥2 heart failure medications
• Documented medication non-adherence
• Able to provide informed consent
• Access to a smartphone

You may not qualify if…

• Severe psychiatric illness
• Terminal illness
• Severe cognitive impairment
• End-stage renal disease
• Participation in another intervention trial

Where it is running

• Civil Hospital Karachi, Dr. Ruth K. M. Pfau Civil Hospital Karachi — Karachi, Pakistan

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.