Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia in Mastectomy

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Breast Cancer

In brief

This study aims to evaluate the effect of serratus posterior superior intercostal plane (SPSIP) block on postoperative pain, opioid consumption, and analgesic requirements in patients undergoing mastectomy and axillary lymph node dissection

Key facts

Study ID

NCT07579650

Run by

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

People needed

50

Starts

2026-05-16

Expected to finish

2026-08-30

Last updated by the study team

2026-07-21

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female patients aged 18-65 years
• ASA physical status I-III
• Scheduled for elective unilateral mastectomy with axillary lymph node dissection under general anesthesia
• Able to understand and use the Numeric Rating Scale (NRS) for pain assessment
• Provided written informed consent

You may not qualify if…

• Known allergy or hypersensitivity to local anesthetics (e.g., bupivacaine)
• Coagulopathy, thrombocytopenia (<100,000/mm³), or ongoing anticoagulant/antiplatelet therapy that cannot be discontinued
• Infection or skin lesion at the injection site
• Planned bilateral surgery or additional major surgical procedures
• Chronic pain conditions or regular use of opioids, gabapentinoids, or centrally acting analgesics
• Neurological or psychiatric conditions interfering with pain assessment
• History of previous major thoracic or chest wall surgery on the same side
• Pregnancy or breastfeeding
• Refusal to participate or inability to provide informed consent

Where it is running

• Fatma Acil — Diyarbakır, Outside of the US, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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