Assessment of Pulmonary Perfusion and Hemodynamic Measurements by Electrical Impedance Tomography in Patients Undergoing Pulmonary Thromboendarterectomy.
Recruiting now · Not applicable
Conditions studied: Pulmonary Thromboendarterectomy, Pulmonary Embolism and Thrombosis
In brief
Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition in which old blood clots block the blood vessels in the lungs, making it harder for the heart to pump blood through the lungs. Surgery called pulmonary thromboendarterectomy can remove these clots and improve blood flow, but doctors need reliable ways to evaluate lung blood flow before and after surgery. This study will evaluate a bedside imaging method called electrical impedance tomography (EIT), which can measure how blood flows through different regions of the lungs without radiation or invasive procedures. Patients undergoing surgery for CTEPH will be monitored with EIT before and after surgery, and the results will be compared with standard lung perfusion imaging. The goal of this study is to determine whether EIT can provide useful information about lung blood flow and changes after surgery, and whether it could serve as a complementary bedside tool to help monitor patients with CTEPH.
Key facts
- Study ID
- NCT07577700
- Run by
- University of Sao Paulo General Hospital
- People needed
- 36
- Starts
- 2025-02-25
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-05-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) followed at the Pulmonology Service of InCor-HCFMUSP and scheduled for pulmonary thromboendarterectomy at InCor-FMUSP.
You may not qualify if…
- Age under 18 years
- Pregnancy
- Structural heart disease (atrial septal defect, ventricular septal defect, or valvular heart disease)
- Cardiac arrhythmias
- Use of a cardiac pacemaker or other implantable electronic device
- Skin lesions on the thoracic region at the site of EIT electrode belt placement
- Absence of central venous access on the day of the preoperative protocol evaluation
- Difficulty understanding the procedures to be performed
- Refusal to participate in the study (non-signing of the Informed Consent Form)
- Refusal by the attending medical team
Where it is running
- Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP — São Paulo, São Paulo, Brazil (enrolling)
Full record on ClinicalTrials.gov
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