Calming Minds Study

Starting soon · Not applicable

Conditions studied: Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts

In brief

The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to: 1. Figure out what actually causes repetitive negative thinking to decrease when people use cognitive-behavioral therapy (CBT). 2. Find out which parts of RNT-focused CBT are the most important - the parts that truly make a difference in reducing RNT. The main result we will look at is how much a person's repetitive negative thought patterns change from the start of the study to the end of treatment (16 weeks). We will measure this using the Perseverative Thinking Questionnaire at baseline and week 16.

Key facts

Study ID

NCT07577401

Run by

University of California, Los Angeles

People needed

500

Starts

2026-06-08

Expected to finish

2028-06-14

Last updated by the study team

2026-05-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 18+ years
• Able to provide a valid Imperial Valley College email address
• Access to a suitable smartphone/device (iPhone 8+ running iOS 16.4 or higher, or Android version 8 or higher)
• Access to internet
• Elevated repetitive negative thought (RNT) based on scores from Ruminative Response Scale Brood subscale (RSS-brood) and Penn State Worry Questionnaire (PSWQ)

You may not qualify if…

• Concurrent psychotherapy
• Self-reported current or past diagnosis or treatment for Psychosis
• Self-reported current or past diagnosis or treatment for Bipolar disorder
• Self-reported current or past diagnosis or currently receiving, or waiting to receive, treatment for substance abuse/dependence
• Self-reported current diagnosis or currently receiving, or waiting to receive, treatment for alcohol abuse/dependence
• Antidepressant/anxiolytic medication that has changed in dose or nature in last 6 weeks
• Current severe PTSD defined as measured by the adapted International Trauma Questionnaire
• Active suicidal thoughts or self-harm

Where it is running

• Imperial Valley College — Imperial, California, United States

Full record on ClinicalTrials.gov

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