False Vocal Fold vs EMG Guided Botox for Vocal Tremor

Starting soon · Not applicable

Conditions studied: Vocal Tremor

In brief

This is a prospective, non-randomized, two-arm comparative clinical trial evaluating outcomes of false vocal fold (FVF) botulinum toxin injections versus standard EMG-guided botulinum toxin injections in patients with essential voice tremor. Participants will receive either FVF injections or EMG-guided injections based on shared clinical decision-making between the treating laryngologist and patient. The study will assess changes in voice-related quality of life, tremor severity, and patient satisfaction over a 12-week follow-up period and compare these outcomes between the two treatment approaches.

Key facts

Study ID

NCT07577310

Run by

University of Alabama at Birmingham

People needed

30

Starts

2026-08-01

Expected to finish

2030-07-01

Last updated by the study team

2026-05-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• Diagnosis of essential voice tremor by a laryngologist and speech pathologist
• Deemed an appropriate candidate for either FVF or EMG-guided botulinum toxin injections
• Able to provide informed consent and complete questionnaires in English

You may not qualify if…

• Coexisting severe neurologic disease that precludes reliable participation in follow-up
• History of laryngeal surgery or structural lesion that markedly confounds tremor assessment
• Known hypersensitivity to botulinum toxin or injectable components
• Pregnancy
• Dysphagia at baseline
• Inability to comply with follow-up schedule

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.