Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults
Starting soon · Not applicable · Has a placebo group
Conditions studied: Frailty Syndrome, Older Adults, Blood Flow Restriction (BFR) Training Effects, Inspiratory Muscle Training
In brief
This randomized controlled trial study aims to evaluate the feasibility and preliminary efficacy of a combined inspiratory muscle training (IMT) and blood flow restriction (BFR) intervention in frail older adults. Outcomes of interest include feasibility, physical function, respiratory muscle strength, handgrip strength, five-times sit-to-stand performance, body composition, frailty level, fall efficacy, blood pressure, and adverse events.
Key facts
- Study ID
- NCT07573995
- Run by
- Taipei Medical University
- People needed
- 30
- Starts
- 2026-05-01
- Expected to finish
- 2026-10-01
- Last updated by the study team
- 2026-05-07
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Community-dwelling adults aged 65 years and older who are classified as at least "vulnerable" using the Clinical Frailty Scale (score ≥4).
- Participants must have no cognitive impairment and be able to follow commands, as assessed by the Mini-Mental State Examination (MMSE).
You may not qualify if…
- (1) are unable to participate in exercise (e.g., due to severe musculoskeletal disorders)
- (2) have high-risk factors for exercise, such as uncontrolled hypertension (>150 mmHg systolic blood pressure (SBP) / >90 mmHg diastolic blood pressure (DBP), coagulation disorders, and deep venous thrombosis
- (3) have hematological disorders or are using hematology related-medications
- (4) have significant comorbidities, including a history of stroke, diabetes with severe complications, or cardiovascular diseases
- (5) chronic lung conditions (e.g., obstructive pulmonary disease, asthma), and
- (6) have participated in a structured exercise training program within the past 3 months at a frequency exceeding three sessions per week.
Where it is running
- Taipei Medical University — Taipei, Taiwan
Full record on ClinicalTrials.gov
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