Proof of Concept for Simulating Static Weight-bearing Exercises in the Supine Position

Starting soon · Not applicable

Conditions studied: Knee Arthroplasty, Total, Healthy Participants

In brief

This project evaluates a new weight-bearing CT method to later improve early detection of implant migration after knee arthroplasty. This method aims to allow patients to apply a controlled load during CT scanning, simulating standing conditions with real-time feedback. The study has two phases. First, in healthy volunteers, biomechanical loading during prone simulated weight-bearing will be compared with a standard standing squat to validate the method. Second, in arthroplasty patients, standard radiographs will be compared with loaded and unloaded WBCT scans. Patients will not deviate from the standard plan of care. The CT images are additions to the standard RX images and are not intended for diagnostic purposes to the patient. The aim is to determine whether this method opens the door for more accurate and earlier detection of implant migration than current clinical imaging in the future, potentially improving long-term outcomes after knee arthroplasty.

Key facts

Study ID
NCT07572292
Run by
Vrije Universiteit Brussel
People needed
15
Starts
2026-05-01
Expected to finish
2026-12-31
Last updated by the study team
2026-05-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

You may not qualify if…

Full record on ClinicalTrials.gov

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