Food and Ethnicity Effects on Pharmacokinetics and Safety of JPI-547 in Healthy Male Participants

Starting soon · Phase 1

Conditions studied: Healthy Volunteers

In brief

This study aims to evaluate the effects of food or ethnicity on the pharmacokinetics and safety/tolerability of JPI-547 after a single oral administration in healthy male Korean, Caucasian, and Chinese participants.

Key facts

Study ID

NCT07570186

Run by

Onconic Therapeutics Inc.

People needed

36

Starts

2026-05-01

Expected to finish

2026-07-01

Last updated by the study team

2026-05-06

Who can join

Age: 19 and older, up to 50. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Healthy Korean, Caucasian, or Chinese male participants aged 19 to 50 years at screening
• Body weight between 50.0 and 90.0 kg and BMI between 18.5 and 29.9 kg/m²
• Able to understand the study and provide written informed consent
• Considered suitable for study participation by the investigator based on medical history, physical examination, and clinical laboratory tests

You may not qualify if…

• Clinically significant medical or surgical history
• Gastrointestinal disease or surgery affecting drug absorption
• Hypersensitivity to PARP inhibitors or other significant drug allergy
• Drug abuse history or positive drug screening
• Clinically significant abnormal vital signs or laboratory results
• Positive viral or serologic screening tests
• Recent use of prohibited medications
• Recent participation in another clinical trial
• Recent blood donation or transfusion
• Inability to abstain from smoking, alcohol, caffeine, or grapefruit
• Failure to comply with contraception or sperm donation requirements
• Any condition making the participant unsuitable in the investigator's judgment

Where it is running

• Seoul National University Hospital — Seoul, South Korea

Full record on ClinicalTrials.gov

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