A Study to Evaluate the Efficacy of a Postbiotic Supplement on Menopausal Symptoms in Premenopausal Women

Completed · Not applicable · Has a placebo group

Conditions studied: Perimenopause, Menopausal Symptoms, Menopause-Related Quality of Life, Microbiome

In brief

The goal of this consumer health study is to evaluate the effect of resW™ Perimenopause Postbiotic on menopausal symptom severity, menopause-related quality of life, and selected microbiome-related outcomes in generally healthy perimenopausal women aged 35 to 55 years. Participants will be randomized to receive either the active supplement or placebo daily for 4 weeks. Participants will complete electronic questionnaires at baseline and during the study. A predefined subset of participants will also complete stool and vaginal sample collection at baseline and Week 4.

Key facts

Study ID

NCT07570043

Run by

Able Biolabs, LLC

People needed

80

Starts

2026-03-04

Expected to finish

2026-05-27

Last updated by the study team

2026-06-01

Who can join

Age: 35 and older, up to 55. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Provide voluntary, signed, and dated informed consent.
• Female, aged 35 to 55 years, inclusive.
• Currently experiencing perimenopausal symptoms, such as hot flashes, mood changes, sleep disturbance, or irregular cycles.
• In generally good health as determined by self-reported medical history.
• Agree to maintain existing diet, exercise, and lifestyle patterns throughout the study period.
• Able and willing to comply with all study procedures, including electronic consent, app-based data entry, and study questionnaires.
• Participants selected for the microbiome substudy must be willing to complete stool and vaginal sample collection.
• Females of childbearing potential must agree to use a medically acceptable form of birth control during the study.
• Agree to refrain from taking other probiotic, prebiotic, postbiotic, hormonal, or menopause-support supplements during the study.
• Have reliable internet or smartphone access.

You may not qualify if…

• Currently pregnant, planning to become pregnant, or breastfeeding.
• History or current diagnosis of gynecologic disorders or other conditions affecting hormonal balance.
• Current or recent use of hormone replacement therapy or hormonal medications.
• History of unstable or newly diagnosed cardiovascular, hepatic, renal, or significant metabolic disorders.
• Known gastrointestinal disease or condition affecting absorption or metabolism.
• Known allergy or sensitivity to any ingredient in the study supplement.
• Current participation in another clinical study involving an investigational product or device, or participation in such a study within the past 30 days.
• Any other medical or psychiatric condition that, in the opinion of the investigator or study team, could interfere with study participation, compliance, or interpretation of study results.

Where it is running

• Able Biolabs LLC — Dallas, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.