Successive Doses of GnRH Agonist Versus Single Dose of GnRH Agonist to Trigger Ovulation in Hyper-responders

Starting soon · Phase 2

Conditions studied: Infertility

In brief

The aim of this randomized controlled study is to compare the efficacy of three successive doses of a GnRH agonist ( administered 36 , 24 and 12 hours before oocyte retrieval ) with a single dose of a GnRH agonist ( administered 36 hours before oocyte retrieval ) in triggering ovulation in hyper-responders

Key facts

Study ID

NCT07569315

Run by

Bedaya Hospital

People needed

190

Starts

2026-06-01

Expected to finish

2028-04-01

Last updated by the study team

2026-05-11

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• GnRH antagonist IVF cycle
• Hyper-responders to induction of ovulation

You may not qualify if…

• Hypogonadotrophic hypogonadism
• Endometriosis
• History of recurrent abortion

Where it is running

• Bedaya Hospital — Giza, Egypt

Full record on ClinicalTrials.gov

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