In Vivo Noradrenergic System and Aging
Recruiting now · Not applicable
Conditions studied: Healthy Aging and Parkinson's Disease
In brief
The main goal of this research proposal is to provide, for the first time in humans, a wider understanding of the role of the noradrenergic system both in health and illness (here Parkinson's disease) through the use of a newly developed radiotracer visualizing alpha2C-ARs (\[11C\]ORM-13070) combined with a cutting-edge technology, the hybrid PET/MRI scanner. The secondary aim will be to determine whether the expected age- and PD-related changes in the noradrenergic system are paralleled by changes in neuropsychological performances (i.e. cognitive, motor and/or olfactory abilities).
Key facts
- Study ID
- NCT07569120
- Run by
- Hospices Civils de Lyon
- People needed
- 165
- Starts
- 2026-06-29
- Expected to finish
- 2029-09-01
- Last updated by the study team
- 2026-07-09
Who can join
Age: 20 and older, up to 80. Sex: any. Healthy volunteers: accepted.
Where it is running
- Hôpital Neurologique Pierre Wertheimer - Service de Neurologie — Bron, France (enrolling)
Full record on ClinicalTrials.gov
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