Research Plan for Early Disease Screening Biomarkers in Healthy Individuals

Starting soon

Conditions studied: Health

In brief

The establishment of reference intervals for biomarkers in healthy populations relies on large-scale, standardized cohort data. However, current baseline data for hematology, liver and kidney function, and multi-omics (genomics, transcriptomics, proteomics, and metabolomics) in Chinese healthy populations are constrained by significant regional disparities and insufficient sample sizes, limiting the development of early disease screening markers. To address these challenges, this study aims to: (1) establish a comprehensive database for hematology and liver/kidney function indicators; (2) construct a multi-omics database using blood and sputum samples; and (3) explore the correlations among multi-omics indicators and their associations with demographic characteristics.

Key facts

Study ID

NCT07569094

Run by

Zhonghao Fang

People needed

300

Starts

2026-05-01

Expected to finish

2027-12-01

Last updated by the study team

2026-05-06

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age: 18 - 65 years old, gender not restricted;
• No clear history of chronic diseases (hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic liver and kidney diseases, tumors, etc.);
• No infection history in the past 3 months (fever, cough, sore throat, etc.);
• No use of antibiotics, hormones, immunosuppressants, etc. within the past 1 month;
• Voluntarily sign the informed consent form and cooperate to complete the follow-up.

You may not qualify if…

• Abnormal laboratory indicators (ALT/AST > 2 times the upper limit of normal value, Cr > upper limit of normal value, main indicators of blood routine test are abnormal and have clinical significance);
• Pregnant or lactating women;
• Recent (within 3 months) history of surgery, trauma or blood transfusion;
• Mental illness or cognitive impairment that makes it impossible to cooperate with the research.

Where it is running

• Fifth Affiliated Hospital of Guangzhou Medical University — Guangzhou, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.