Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age
Starting soon · Not applicable
Conditions studied: Aging, Postural Balance, Accidental Falls
In brief
This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control group. The primary outcome is balance function measured by the Berg Balance Scale. Secondary outcomes include physical function, psychological well-being, cognitive function, and sleep quality. The study also explores the predictive and modifying roles of baseline circadian age on intervention outcomes.
Key facts
- Study ID
- NCT07567976
- Run by
- Zhide Liang
- People needed
- 90
- Starts
- 2026-06-01
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-07-02
Who can join
Age: 55 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Aged 55 years or older
- Community-dwelling
- Able to walk independently (assistive devices such as canes are permitted)
- Berg Balance Scale (BBS) score ≤52 at screening
- Able to understand and follow verbal instructions
- Willing to wear a wrist accelerometer continuously for 7 days at baseline
- Willing to accept random group assignment
- Willing to undergo blood collection during the study
- Provides written informed consent
You may not qualify if…
- Regular Tai Chi or yoga practice (more than once per week) within the past 6 months
- Severe cognitive impairment (Montreal Cognitive Assessment [MoCA] score <20 at screening, or previously diagnosed dementia)
- Unstable cardiovascular disease (myocardial infarction, stroke, or hospitalization within the past 3 months)
- Severe musculoskeletal disease that limits exercise participation
- Neurological diseases affecting balance (e.g., Parkinson's disease, severe peripheral neuropathy)
- Currently participating in another exercise intervention study
- Planned surgery or extended absence during the study period
- Contraindications to functional near-infrared spectroscopy (fNIRS) examination (e.g., scalp injury, metallic implants in the head region)
- Severe psychiatric illness (e.g., schizophrenia, bipolar disorder)
- Considered unable to safely participate in moderate-intensity physical activity as judged by the study physician or attending healthcare provider
Full record on ClinicalTrials.gov
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