A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity

Recruiting now · Phase 1 · Has a placebo group

Conditions studied: Obesity, Overweight

In brief

The purpose of this clinical study is to find out if NNC0113-5840 is safe for treating people with excess body weight. There are 2 study treatments in this study, participants will get either NNC0113-5840 (the product being tested) or Placebo (treatment that has no active medicine in it), Which treatment participants get is decided by chance.

Key facts

Study ID

NCT07566390

Run by

Novo Nordisk A/S

People needed

48

Starts

2026-05-01

Expected to finish

2026-12-26

Last updated by the study team

2026-08-04

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female
• Age 18-55 years (both inclusive) at the time of signing the informed consent.
• Body mass index (BMI) between 25.0 and 34.9 kilogram per meter square (kg/m2) (both inclusive) at screening. Overweight should be due to excess adipose tissue, as judged by the investigator.
• Considered eligible based on the medical history, physical examination, and the results of vital signs, electrocardiogram and clinical laboratory tests performed during the screening visit and visit 2, day -1, as judged by the investigator.

You may not qualify if…

• Known or suspected hypersensitivity to study intervention(s) or related products.
• Any condition, which in the investigator's opinion might jeopardise participant's safety or compliance with the protocol.
• Glycosylated haemoglobin (HbA1c) more than or equal to (≥) 6.5 percent (%) [48 millimole per mole (mmol/mol)] at screening.

Where it is running

• PAREXEL Glendale/LA EPCU — Glendale, California, United States (enrolling)
• PAREXEL Intl - EPCU-Baltimore — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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