Effect of Lemon Juice and Apple Cider Vinegar on Postprandial Blood Glucose and Satiety in Healthy Individuals

Recruiting now · Not applicable

Conditions studied: Satiety, Postprandial Glycemia

In brief

This clinical study aims to examine how acidic drinks (lemon juice and apple cider vinegar) affect blood sugar when consumed with a starchy food. The study focuses on healthy individuals and aims to understand whether these drinks can slow the rise in blood sugar after meals and affect feelings of fullness. The main questions this study aims to answer are: Do lemon juice or apple cider vinegar lower the rise in blood sugar after a meal? Do these drinks increase feelings of fullness? Do different amounts change their effects? Researchers will compare lemon juice and apple cider vinegar to see which one is more effective. Participants will: Consume white bread in the morning on an empty stomach with one of the following drinks: Water only Water with lemon juice (50 g or 100 g) Water with apple cider vinegar (10 g or 20 g) Have a one-week break between each test. Have their blood sugar measured at regular intervals for 3 hours after eating. Report their level of fullness using a simple scale. This study explores whether simple and practical dietary choices can help manage blood sugar levels. The findings may support new, easy-to-apply nutrition strategies for managing diabetes and weight.

Key facts

Study ID

NCT07563985

Run by

Alanya Alaaddin Keykubat University

People needed

15

Starts

2026-05-01

Expected to finish

2026-07-01

Last updated by the study team

2026-05-04

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy male and female volunteers aged 18-35 years
• Body Mass Index (BMI) between 18.5 and 25.0 kg/m²
• Willingness to provide written informed consent
• Ability to comply with study procedures and fasting requirements
• No history of chronic metabolic, gastrointestinal, or endocrine diseases

You may not qualify if…

• Presence of any chronic disease (e.g., diabetes mellitus, cardiovascular disease, gastrointestinal disorders)
• Food allergies or intolerances to study foods (white bread, lemon juice, apple cider vinegar)
• BMI <18.5 or >25.0 kg/m²
• Regular participation in high-intensity physical activity (≥5 days/week)
• Current or recent (past 3 months) smoking or smoking cessation
• Use of any medication or supplements affecting glucose metabolism
• History of eating disorders
• Pregnancy, lactation, or menopause
• Female participants currently in menstruation period (testing will be postponed during menstruation days)
• Alcohol consumption within 24 hours prior to testing days
• Caffeine intake or major dietary changes on the day before testing

Where it is running

• Alanya Alaaddin Keykubat University — Alanya, Antalya, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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