Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

Running, not enrolling · Not applicable

Conditions studied: Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)

In brief

The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial. The main questions this study aims to answer are: 1. If MM's 12-week EDC intervention program (EDC testing and report-back, EDC reduction curriculum) can reduce weight? 2. If a 12-week validated digital weight loss program can reduce EDC exposures? 3. What is the effectiveness of the two interventions at reducing weight and urinary EDC metabolites? Participants will be assigned to one of these two arms. Participants will collect their urine and blood samples pre- and post-intervention, and will take a comprehensive exposure survey before sending back their samples. This exposure survey will ask about participant's weight loss literacy, environmental health literacy, product use, diet, and lifestyle behaviors.

Key facts

Study ID

NCT07560579

Run by

Million Marker Wellness, Inc.

People needed

226

Starts

2025-08-18

Expected to finish

2026-09-01

Last updated by the study team

2026-05-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• BMI over 25
• Not pregnant or breast feeding
• Do not have diabetes, kidney disease, liver disease, cardiac disease, pulmonary disease or cancer.
• Do not smoke
• Not in another weight loss program or on GLP-1
• Have access to a smartphone or computer

You may not qualify if…

• BMI under 25
• Pregnant or breast feeding
• Have diabetes, kidney disease, liver disease, cardiac disease, pulmonary disease or cancer.
• Smoke
• In another weight loss program or on GLP-1
• Do not have access to a smartphone or computer

Where it is running

• Million Marker — Berkeley, California, United States

Full record on ClinicalTrials.gov

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