Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery

Recruiting now

Conditions studied: Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases

In brief

In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB will accelerate recovery. Additionally, it is anticipated that RIFB, an alternative fascial plane block, will demonstrate non-inferior (at least as effective as) performance compared to RSB, thereby providing flexibility and ease of application in clinical practice.

Key facts

Study ID

NCT07557108

Run by

Ordu University

People needed

123

Starts

2026-04-05

Expected to finish

2026-12-20

Last updated by the study team

2026-05-04

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who have provided written informed consent
• Open-heart surgery performed under elective conditions via median sternotomy with cardiopulmonary bypass (on-pump)
• American Society of Anesthesiologists (ASA) physical status class II or III
• Aged 18-70 years

You may not qualify if…

• Off-pump surgical procedure
• Emergency or repeat cardiac surgery
• Known allergy to induction agents or local anesthetics
• Body mass index (BMI) >35 kg/m²
• Coagulopathy
• Infection at the surgical site
• Left ventricular ejection fraction (LVEF) <40%
• Renal insufficiency (estimated glomerular filtration rate <60 mL/min/1.73 m²) or hepatic insufficiency [Presence of major systemic diseases such as acute decompensated cirrhosis characterized by bilirubin >12 mg/dL, INR >2.5, or hepatic encephalopathy, in accordance with the European Association for the Study of the Liver-Chronic Liver Failure Consortium criteria]
• Psychiatric disorders
• History of chronic pain or regular use of analgesics (corticosteroids, analgesics, anticonvulsants)
• Cognitive impairments that could interfere with the assessment of postoperative pain
• Patients with impaired physical and verbal performance

Where it is running

• Name: Ordu University Training and Research Hospital — Ordu, Altinordu, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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