Optimal Protein Intake to Maximize Whole-Body Protein Balance in Healthy Adults
Starting soon · Not applicable
Conditions studied: Protein Metabolism
In brief
The purpose of this study is to assess the optimal protein intake to maximize whole-body protein net balance in healthy adults. In a randomized, double-blinded, crossover design, 12 young, healthy adult males and females aged 18-35 years, will consume a test diet consisting of free amino acid mixtures based on milk protein that vary in protein content 7 separate acute metabolic trials. The main study endpoint is optimal protein intake based on the lowest protein intake that maximizes whole-body protein net balance.
Key facts
- Study ID
- NCT07556029
- Run by
- Maastricht University Medical Center
- People needed
- 12
- Starts
- 2026-08-01
- Expected to finish
- 2027-04-01
- Last updated by the study team
- 2026-04-29
Who can join
Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Aged between 18-35 years
- BMI between 18.5-30 kg/m2
- Healthy, recreationally active (exercise at least once per two weeks and a maximum of four days per week)
- No physical limitations (i.e., able to perform all activities associated with daily living independently)
You may not qualify if…
- Smoking
- Diagnosed musculoskeletal disorders
- Use of any medications known to affect protein metabolism (i.e., corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications)
- Chronic use of gastric acid-suppressing medication or anti-coagulants
- Unstable weight over the last three months
- Diagnosed GI tract disorders or diseases
- Blood donation in the past 2 months
- Females: pregnancy
Where it is running
- Maastricht University Medical Centre+ — Maastricht, Limburg, Netherlands
Full record on ClinicalTrials.gov
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