Nonoinvasive HPI in Beach-chair Position

Starting soon · Not applicable

Conditions studied: the Intraoperative Hypotensionn, the Brain Exygenation

In brief

Intraoperative hypotension (defined as mean arterial pressure \<65 mmHg) is a common occurrence during anesthesia and has been associated with increased risk of intraoperative hypoxia and postoperative complications, including stroke and acute kidney injury. Preventing intraoperative hypotension is therefore critical to reducing postoperative morbidity. The number of patients undergoing arthroscopic shoulder surgery has been increasing. When performed in the beach chair position, gravitational effects reduce venous return, decrease cardiac output, and predispose patients to hypotension. Anesthetic agents further impair autonomic regulation and vascular tone, exacerbating the risk. Because the brain is positioned above the heart, cerebral perfusion pressure may decrease significantly, increasing the risk of intraoperative ischemia and postoperative neurological complications. Active monitoring and prevention of hypotension are thus essential. The noninvasive Hypotension Prediction Index (HPI) is a novel, non-invasive tool designed to predict impending hypotensive events and guide timely intervention. While it has been evaluated in some small randomized controlled trials, there is currently a lack of RCTs specifically assessing the use of non-invasive HPI-guided management in patients undergoing arthroscopic shoulder surgery in the beach chair position.

Key facts

Study ID: NCT07554599
Run by: National Taiwan University Hospital
People needed: 60
Starts: 2026-04-27
Expected to finish: 2032-01-31
Last updated by the study team: 2026-05-08

Who can join

Age: 65 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Non-emergent shoulder arthroscopy performed in the beach chair position, with eligibility criteria including male or female patients aged 65-90 years.

You may not qualify if…

Women who are pregnant, planning to become pregnant during the study period, or breastfeeding
Individuals with major cardiac diseases, such as severe arrhythmia or heart failure
Individuals with significant renal disease, e.g., chronic renal failure requiring dialysis
Individuals with a history of stroke
Individuals diagnosed with dementia

Full record on ClinicalTrials.gov

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