Comparison of Radiological Outcome of Conventional vs Accelerated Ponseti Casting Technique for Treatment of Club Foot

Recruiting now · Not applicable

Conditions studied: Club Foot

In brief

Club foot (congenital talipes equinovarus) is a common birth deformity affecting 1-2 per 1,000 live births, with even higher rates in low-income countries. The standard treatment is the Ponseti method using weekly serial casts, but weekly visits for several weeks can be challenging for families in hot climates or with limited resources. This randomized controlled trial compares the standard once-weekly Ponseti casting with an accelerated twice-weekly casting technique. The primary outcome is radiological correction measured by the lateral talocalcaneal angle (target ≥35°) on standardized foot X-rays taken six weeks after brace fitting. Secondary outcomes include the talocalcaneal index (\>40) and the tibio-calcaneal (dorsiflexion) angle (60-90°). Babies under six months of age with idiopathic club foot will be randomly assigned to either the standard or accelerated casting group. All other aspects of the Ponseti method (manipulation, number of casts, tenotomy when needed, final cast for three weeks, and foot abduction orthosis) remain identical. Adverse events such as skin problems, swelling, or cast complications will be recorded. The study aims to determine whether accelerated casting achieves better radiographic correction without increasing risks.

Key facts

Study ID

NCT07554092

Run by

Khyber Medical University Peshawar

People needed

144

Starts

2026-02-01

Expected to finish

2026-11-25

Last updated by the study team

2026-04-28

Who can join

Age: 0 and older, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Both gender with idiopathic club foot with age less than 6 months

You may not qualify if…

• Syndromic club foot (e.g., associated with arthrogryposis, myelomeningocele, or other genetic syndromes)
• Previous treatment for club foot (either serial casting or surgical intervention)
• Any other significant congenital anomaly or medical condition that, in the opinion of the investigator, would interfere with treatment or follow-up

Where it is running

• Khyber Teaching Hospital — Peshawar, KPK, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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