A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran

Recruiting now · Phase 2 · Has a placebo group

Conditions studied: Hypertension

In brief

The purpose of this study is to evaluate the efficacy, pharmacodynamics (PD), and safety of ALN-AGT01 RVR in participants with mild to moderate hypertension pretreated with zilebesiran.

Key facts

Study ID

NCT07553442

Run by

Alnylam Pharmaceuticals

People needed

93

Starts

2026-04-27

Expected to finish

2028-10-01

Last updated by the study team

2026-07-23

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Clinical Trial Site — Lake Forest, California, United States (enrolling)
• Clinical Trial Site — Tampa, Florida, United States (enrolling)
• Clinical Trial Site — Savannah, Georgia, United States (enrolling)

Full record on ClinicalTrials.gov

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