Sebum Metabolomics and Lipidomics for Clinical Applications
Starting soon · Not applicable
Conditions studied: Acne, Atopic Dermatitis, Seborrheic Dermatitis, Psoriasis, Healthy Subjects (HS)
In brief
This study aims to develop a standardized workflow for sebum sampling and metabolomics/lipidomics analysis using Sebutape. A total of 200 participants will be recruited, including healthy individuals, patients with skin diseases, individuals undergoing dermatological treatments or using skincare products, and a subset of healthy participants receiving short-term topical antibiotic intervention. The study will investigate sebum composition, skin microbiome profiles, and their interactions under different conditions to explore potential biomarkers and clinical applications.
Key facts
- Study ID
- NCT07549828
- Run by
- National Taiwan University Hospital
- People needed
- 200
- Starts
- 2026-04-01
- Expected to finish
- 2029-03-31
- Last updated by the study team
- 2026-04-24
Who can join
Age: 20 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be in good health and suitable for participation.
- No diagnosed skin diseases or chronic systemic diseases.
- No use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
You may not qualify if…
- Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
- Presence of acute or chronic skin diseases, or chronic systemic diseases.
- Use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
- Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
- Any other conditions deemed unsuitable for participation by the principal investigator.
- B. Participants with Skin Diseases or Specific Skin Conditions
- Inclusion Criteria:
- Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be suitable for participation.
- Diagnosed by a physician or clinically assessed as having one of the following:
- Acne
- Atopic dermatitis
- Seborrheic dermatitis
- Psoriasis
- Other common skin diseases
- Specific skin conditions (e.g., postmenopausal or aging-related skin changes)
- Exclusion Criteria:
- Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
- Severe disease that may compromise skin integrity or pose a risk to participant safety.
- Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
- Any other conditions deemed unsuitable for participation by the principal investigator.
- C. Participants Receiving Dermatological Treatments or Using Skincare Products
- Inclusion Criteria:
- Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be suitable for participation.
- Participants who, based on clinical needs or daily routines, are currently using or are expected to use or receive any of the following:
- Physician-prescribed topical dermatological medications
Full record on ClinicalTrials.gov
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