Is Professional Tooth Cleaning Necessary for Managing Gingivitis (Gingival Inflammation) if Subjects Use Intelligent Toothbrushes?

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Gingivitis, Periodontitis

In brief

Periodontitis is highly prevalent and develops from plaque-induced gingivitis. Managing gingivitis is key to preventing periodontitis and its complications. Professional mechanical plaque removal (PMPR) with oral hygiene guidance is effective for gingivitis, but large-scale implementation-especially in China-faces challenges such as workforce shortages. Meanwhile, patient compliance with daily oral hygiene remains poor. An optimal oral care regimen featuring an intelligent electric toothbrush (i-Brush) has shown promise in enhancing self-care adherence and efficiency. However, it remains unclear whether PMPR is still necessary when used in conjunction with this optimal oral care regimen. This study aims to verify whether the i-Brush-based regimen is non-inferior to the combination of PMPR and the regimen in improving gingival inflammation in gingivitis and stage I periodontitis.

Key facts

Study ID

NCT07549347

Run by

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

People needed

92

Starts

2026-03-09

Expected to finish

2027-03-01

Last updated by the study team

2026-04-24

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≧18 years old and < 65 years old
• Gingivitis, Stage I and Localized Stage II Periodontitis
• With more than 20 teeth
• Agree to use the electronic I-brush with the Oral-B APP

You may not qualify if…

• Presence of any systemic disease that can alter the outcome of periodontal treatment
• Pregnancy or lactation during the study
• Having received antibiotics within the previous 3 months
• Having received professional periodontal treatment within the previous 3 months
• With ongoing orthodontic treatment

Where it is running

• Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine — Shanghai, Shanghai Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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