Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo"
Starting soon · Phase 2
Conditions studied: Vitiligo - Macular Depigmentation
In brief
This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo. It aims to evaluate both clinical and histopathological outcomes in 30 patients with non-segmental stable vitiligo. Vitiligo is a chronic depigmenting disorder caused by melanocyte destruction with significant psychosocial impact. The study also investigates immunohistochemical changes, particularly Wnt/β-catenin signaling expression in lesional skin. The combination therapy is expected to enhance repigmentation by improving melanocyte activation, drug delivery, and angiogenesis
Key facts
- Study ID
- NCT07548918
- Run by
- Sohag University
- People needed
- 30
- Starts
- 2026-05-20
- Expected to finish
- 2027-10-15
- Last updated by the study team
- 2026-04-29
Who can join
Age: 16 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients with stable non-segmental vitiligo
- No new lesions
- No enlargement of existing lesions
- Patients of both sexes
- Age 16 years or older
You may not qualify if…
- Active vitiligo
- Pregnant or lactating women
- History of keloid formation
- Hematological disorders
- Coagulopathies
- Use of anticoagulant therapy
- Use of medications that may prolong bleeding
- Previous vitiligo treatment in the last 2 months
Full record on ClinicalTrials.gov
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