Comparison of Transphyseal Screws and Eight Plates in Hemiepiphysiodesis for Coronal Knee Deformities: Short-Term Results

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Conditions studied: Coronal Deformities Around the Knee

In brief

Coronal angular deformities of the lower limbs, such as bow legs and knock-knees, are frequently observed in childhood. While many cases are considered normal and resolve on their own, when these deformities become significant and progressive, they can disrupt the quality of life, leading to gait disturbances, pain, and in severe instances, joint instability. Additionally, these deformities may have indirect effects on other joints like the hip and ankle, and most importantly, they increase the risk of early osteoarthritis in the knee . It is generally accepted that a significant deformity that persists up to preadolescence will not correct spontaneously. Physiological alignment of the lower limb is crucial for the symmetrical distribution of weight over the surfaces of the joints, especially the knee. Indeed, severe coronal malalignment has been linked to knee pain, altered gait, and occasionally patellofemoral problems .

Key facts

Study ID

NCT07548749

Run by

Sohag University

People needed

60

Starts

2026-05-01

Expected to finish

2027-04-01

Last updated by the study team

2026-04-23

Who can join

Age: 3 and older, up to 14. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Both gender (males and females)
• Children ≥3 years old and growing children 2 years at least remaining in growth ( skeletal immature)
• Cases with progressive knee deformities around knee at any side.

You may not qualify if…

• 1. Physeal closure.
• Physiological deformity in younger ages that could be managed conservatively ( age < 3 years )
• Cases with metabolic or chronic illness conditions unresolved.

Where it is running

• Sohag faculty of medicine — Sohag, Egypt

Full record on ClinicalTrials.gov

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