Evaluation of the Efficacy and Safety of Palmitoleic Acid Oil Composition in Preventing Pressure Injuries

Enrolling by invitation · Not applicable

Conditions studied: Pressure Ulcer Prevention

In brief

To evaluate the efficacy and safety of a topical palmitoleic acid (POA) oil composition in preventing PIs and reversing Stage I damage using an integrated physiological monitoring approach.

Key facts

Study ID

NCT07547254

Run by

Ruijin Hospital

People needed

60

Starts

2025-12-01

Expected to finish

2026-12-01

Last updated by the study team

2026-04-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult inpatients (aged above 18 years).
• High risk for sacral pressure injuries, objectively defined by an abnormal hydration status (Sacral Subepidermal Moisture [SEM] Delta > 0.5) at screening.

You may not qualify if…

• Medical contraindications to standard repositioning protocols (e.g., unstable pelvic fractures).
• Use of topical medications or advanced prophylactic dressings on the sacrum within 14 days prior to enrollment.
• Active peripheral vascular disease significantly impairing local tissue perfusion.
• Documented hypersensitivity to the investigational product (POA) or its vehicle components.

Where it is running

• Ruijin Hospital, Shanghai Jiaotong University School of Medicine — Shanghai, Shanghai Municipality, China

Full record on ClinicalTrials.gov

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