Peer-led Service Delivery Model for Pregnant and Lactating Adolescent Girls and Young Women in Zimbabwe
Starting soon · Not applicable
Conditions studied: HIV Prevention, Contraceptive Usage, Adherence, Medication
In brief
This is a pilot cluster-randomized control trial co-led by Dr. Valentina Cambiano, Associate Professor of Epidemiology at University College London, UK and Professor Euphemia Sibanda, Research Director at the Centre for Sexual Health and HIV Research (CeSHHAR Zimbabwe). The goal of the proposed study is to evaluate the appropriateness, feasibility, acceptability, uptake, costs and cost-effectiveness of a community-based, HIV-status neutral peer-led service delivery model in which young mentor mothers (YMM) work with pregnant and lactating adolescent girls and young women (PL-AGYW, aged 15-24), up to two-years post-birth, in Zimbabwe to promote uptake of contraception and HIV prevention. YMM living with HIV have been found to be effective in supporting their peers for prevention of mother-to-child transmission of HIV and adherence to treatment through the "Zvandiri" programme. The investigators propose adapting the "Zvandiri" YMM to include those without HIV to promote behaviour to prevent HIV and unintended pregnancies. This proposed intervention is building on the formative work that had the overall aim of co-developing with AGYW (aged 15-24) a Pre-Exposure Prophylaxis (PrEP) implementation intervention for AGYW who need it, that attracts them to PrEP, and supports pregnant and lactating adolescent girls and young women while taking it.
Key facts
- Study ID
- NCT07546344
- Run by
- University College, London
- People needed
- 600
- Starts
- 2026-04-01
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-04-22
Who can join
Age: 15 and older, up to 24. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- either pregnant or have at least one child who is less than 18 months of age at the time of initial engagement
- Aged 15 - 24 years old
Where it is running
- Shangani Rural Hospital — Shangani, Insiza, Zimbabwe
- Empandeni clinic — Empandeni Mission, Matabeleland South Province, Zimbabwe
- Mawabeni Clinic — Mawabeni, Matabeleland South Province, Zimbabwe
Full record on ClinicalTrials.gov
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