Transradial vs Transfemoral Group-Randomized Efficacy and Safety Trial for Cerebral Angiography
Starting soon · Not applicable
Conditions studied: Cerebrovascular Disease
In brief
This study will compare the efficacy and safety of the transradial approach versus the transfemoral approach for performing full cerebral angiography. Participants will undergo cerebral angiography via one of the two approaches and will be followed up during and after the procedure. The primary endpoint of this study is to evaluate the success rate of completing full cerebral angiography (including superselective catheterization of bilateral common carotid arteries, subclavian arteries near the vertebral artery origin, and the aortic arch) via the transradial approach versus the transfemoral approach. During the study, the medical team will also document procedural details, incidence of complications, patient comfort, and related costs to comprehensively evaluate the clinical performance differences between the two approaches.
Key facts
- Study ID
- NCT07544043
- Run by
- Gansu Provincial Maternal and Child Health Care Hospital
- People needed
- 2473
- Starts
- 2026-05-01
- Expected to finish
- 2027-05-01
- Last updated by the study team
- 2026-04-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age > 18 years;
- Patients requiring full cerebrovascular angiography;
- Objective evidence indicates the patient is suitable for transfemoral or transradial cerebrovascular angiography, with upper limb vascular ultrasound 4.showing a radial artery internal diameter ≥ 1.5 mm;
- Modified Rankin Scale (mRS) score ≤ 2 points; 6.Signed informed consent form.
You may not qualify if…
- Positive right Allen's test/Barbeau test; femoral artery occlusion (for the TFA group);
- Local infection or trauma at the puncture site;
- Coagulation abnormalities: INR > 1.5 or platelet count < 50 × 10⁹/L;
- Presence of access vessel disease or anatomical variation deemed potentially hazardous to the subject, such as aortic arch interruption, subclavian artery occlusion, or aortic dissection;
- Pregnancy;
- Planned or recent (within the past 2 weeks) major surgery or severe trauma;
- Expected survival less than 5 years;
- Severe cardiac, hepatic, renal, or other organ dysfunction;
- Contraindication to contrast agents used in cerebrovascular angiography;
- Inability to comply with follow-up.
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.