Breathing Patterns in Infants Before and After Extubation

Recruiting now

Conditions studied: Respiratory Distress Syndrome (RDS), PreTerm Neonate

In brief

The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spontaneous breathing tests (SBTs) in intubated premature infants admitted to the ChristianaCare NICU.

Key facts

Study ID

NCT07542301

Run by

Christiana Care Health Services

People needed

30

Starts

2025-04-14

Expected to finish

2026-12-01

Last updated by the study team

2026-04-21

Who can join

Age: any, up to 1. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• premature infants (born at ≤32 weeks gestation) who are intubated.
• medical team is evaluating the baby for extubation readiness

You may not qualify if…

• Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of RIP measurements will be excluded.

Where it is running

• ChristianaCare Health Services, Inc. — Newark, Delaware, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.