Effects of Berberine on Cardiometabolic Outcomes

Starting soon · Not applicable · Has a placebo group

Conditions studied: Cardiometabolic Syndrome

In brief

Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount. Dietary interventions to improve cardiometabolic health are highly sought after as they possess less risk than pharmacological drugs. It has been postulated that Berberine may be beneficial in improving cardiometabolic outcomes. However, to date, no research has explored this using a placebo randomized intervention.

Key facts

Study ID

NCT07541898

Run by

University of Central Lancashire

People needed

40

Starts

2026-07-01

Expected to finish

2029-01-01

Last updated by the study team

2026-04-21

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy
• Between 18 \& 65 years
• Non-smoker
• BMI < 30
• Able to give informed consent

You may not qualify if…

• Pregnancy
• Diabetes or any other metabolic/ uncontrolled hypertensive conditions
• Food allergies to berberine
• Habitual consumption of berberine
• Not regularly taking medication or antioxidant supplements

Full record on ClinicalTrials.gov

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