Dipotassium Oxalate for Postoperative Sensitivity in NCCLs

Starting soon · Not applicable

Conditions studied: Dentin Hypersensitivity, Post Operative Sensitivity Control

In brief

Postoperative sensitivity is a common complication following Class V composite restorations, particularly in non-carious cervical lesions (NCCLs). This randomized controlled trial aims to evaluate the effectiveness of dipotassium oxalate as a pre-treatment agent in reducing postoperative sensitivity. A total of 64 participants will be randomly assigned into two groups: an intervention group receiving dipotassium oxalate prior to adhesive application, and a control group receiving standard adhesive protocol without pretreatment. Sensitivity will be assessed using a Visual Analog Scale (VAS) in response to cold and air stimuli at baseline, 24 hours, 7 days, and 30 days. The study aims to determine whether dipotassium oxalate significantly reduces postoperative sensitivity and can be incorporated into routine restorative dental practice.

Key facts

Study ID

NCT07540299

Run by

Postgraduate Medical Institute, Lahore

People needed

64

Starts

2026-06-01

Expected to finish

2026-10-01

Last updated by the study team

2026-04-22

Who can join

Age: 30 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals aged 30 to 45 years.
• Presence of at least one tooth with a non-carious cervical lesion (Class V) with a lesion depth of ≥1 mm, requiring restorative treatment.
• The NCCL must show some symptoms/signs of pre-op sensitivity on applying stimulus (i.e Air burst / ethyl chloride spray) and will be recorded.
• The involved teeth must be vital and show no signs or symptoms of irreversible pulpitis or necrosis.
• Subjects must be willing to provide written informed consent and commit to the study's follow-up schedule.
• Subjects with fair to good oral hygiene as determined by a simplified oral hygiene index (OHI-S score ≤2).

You may not qualify if…

• Presence of carious lesions or restored teeth with existing secondary caries
• Any tooth with pulpal involvement, previous root canal therapy, or periapical pathology.
• Teeth with chronic periodontal disease( BPE score 3 and above.).
• Individuals regularly using Desensitizing toothpastes, NSAIDs, antidepressants, or any other pain-modulating drugs that may alter sensitivity reporting.

Where it is running

• Punjab Dental Hospital, Lahore — Lahore, Punjab Province, Pakistan

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.