Co-supplementation With Bifidobacterium Longum W11 and Colopectin for Maintenance Therapy in Children With Functional Constipation

Starting soon · Not applicable · Has a placebo group

Conditions studied: Functional Constipation

In brief

Functional constipation is a common condition in children and often requires prolonged maintenance treatment with macrogol. This randomized, double-blind, placebo-controlled trial will evaluate whether co-supplementation with Bifidobacterium longum W11 and Colopectin can support maintenance therapy in children with functional constipation who are receiving macrogol and are candidates for weaning. Participants aged 2 to 6 years will be randomized to receive either the active supplementation or placebo once daily for 4 weeks, followed by 4 weeks of follow-up after treatment discontinuation. The study will assess persistence of constipation after macrogol discontinuation, as well as stool consistency, distress during evacuation, soiling episodes, and treatment compliance.

Key facts

Study ID

NCT07536698

Run by

Liaquat University of Medical & Health Sciences

People needed

100

Starts

2026-04-20

Expected to finish

2027-05-17

Last updated by the study team

2026-04-17

Who can join

Age: 2 and older, up to 6. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children aged 2 to 6 years
• Diagnosis of functional constipation
• Receiving maintenance therapy with macrogol for at least 3 months
• Candidates for weaning from macrogol therapy

You may not qualify if…

• Children with intestinal meteorism or flatulence
• Children diagnosed with organic constipation
• History of previous abdominal surgery
• Children with frailty or disabilities
• Presence of other organ diseases or syndromes

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.